Tuesday, February 28, 2012
About CJC-1295
CJC-1295 was developed for clinical trials in the year 2000. The drug was originally synthesized to remove visceral fat deposits in AIDS patients. CJC 1295 was ultimately successful on all research subjects, as increasing the level of growth hormone in the body proved to increase fat loss.
Various experiments have been conducted to test the effectiveness of CJC-1295 in vivo and the Journal of Clinical Endocrinology & Metabolism has reported dose-dependent increases in mean plasma GH concentrations by 2-10 fold for more than 6 days and increased IGF-1 concentrations 1.5-3 fold for 9-11 days after a single injection.
Not only that but they proved the mean half life to be 5.8-8.1 days and after multiple doses showed mean IGF-1 levels remained above baseline for up to 28 days following! No serious adverse reactions were reported in any group.
Another very positive benefit of CJC-1295/CJC-1293 is its ability to promote slow wave sleep. Slow wave sleep is also known as deep sleep and is the portion of sleep responsible for the highest level of muscle growth and memory retention. SWS are decreased significantly in older adults and also with people who tend to exercise later in the evening.
Sunday, February 26, 2012
About GHRP-6 (2)
GHRP-6 stands for “growth hormone releasing peptide”. As the name suggests, the product works by stimulating the body to release more Human Growth Hormone (HGH) and IGF-1. HGH and IGF-1 levels decline rapidly as one gets older, and it is this decline which is thought to be responsible for the aging process. Besides a much lower cost, GHRP-6 offers another distinct advantage over HGH injections as it does not shut down the body’s natural production of this hormone, it just enhances it.
Compared to GHRP-2, GHRP-6 is more attractive because at the recommended dosage it does not lead to desensitization and therefore diminishing effect over time as can happen with GHRP-2.
Possible benefits: Fat loss, muscle gain, increased strength, improved skin tone, better sleep, more energy, stronger bones and connective tissues.
Useful for: Bodybuilders looking to gain muscle; Ordinary people looking to lose fat; older persons looking for anti-aging benefits.
Use it before bed and/or post workout. Taken on an empty stomach (at least 2 hours since last meal), then wait at least 20-30 minutes after your injection before eating.
Works by subcutaneous injection into fat. It can be simultaneously injected in the same syringe as other peptides.
Description:
Growth Hormone Releasing Peptide-6 Synthetic is a single, non-glycosylated polypeptide chain containing 6 amino acids, having a molecular mass of 873 Dalton and a Molecular formula of C46H56N12O6.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Solubility:
It is recommended to reconstitute the lyophilized GHRP-6 in sterile 18MO-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Thursday, February 23, 2012
About GHRP-6 (1)
In the world of bodybuilding, GHRP-6 is useful as it facilitates enhancements in terms of normal pulsatile physiological secretion by its hypothalamic action and pulsatile secretory bursts of GH. The list of benefits also include improved natural production of growth hormone, sound sleep, sense of well being, and fast healing of joints and tendons.
GHRP-6 stands for “growth hormone releasing peptide”. As the name suggests, the product works by stimulating the body to release more Human Growth Hormone (HGH) and IGF-1. HGH and IGF-1 levels decline rapidly as one gets older, and it is this decline which is thought to be responsible for the aging process. Besides a much lower cost, GHRP-6 offers another distinct advantage over HGH injections as it does not shut down the body’s natural production of this hormone, it just enhances it.
This peptide has a strong effect on the body's release of GH. It almost promotes hunger and appetite by stimulating a release in Ghrelin which is a peptide in the stomach which promotes appetite and gastric emptying. GHRP-6 acts by stimulating the anterior pituitary gland which causes an increased released of GH. GHRP-6 is used for a range of medical issues including low natural GH production and to promote weight gain in abnormally thin individuals.
Labels:
energy,
fat loss,
GHRP-6,
HGH,
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muscle,
peptide,
side effects,
sleep quality
Wednesday, February 22, 2012
Melanotan (2)
To get a visibly flawless skin, you must know about this peptide as how it can provide you an exquisitely beautiful skin. Melanotan 1 is basically a synthetic derivative of its own natural counterpart called alpha-melanocyte-stimulating hormone (a-MSH).
The presence of two amino acids in the bodies natural a-MSH are converted in the production of Melanotan 1 increasing stability. The melanotropin peptides to a larger extent can influence pigmentation in the body. If melanotan peptide therapy is combined with UV-B light, it stimulates melanocytes production of melanin and specifically the production of eumelanin. Melanin works effectively in absorbing, reflecting and refracting light to preventing cellular damage in the skin. It also transforms cells to produce dark protective melanin which ultimately helps in reducing sun damage done to UV exposed skin. On the other hand, eumelanin is produced over pheomelanin pigment that after injecting offers greater tanning ability levels. However, melanotan only works when injected below the skin (subcutaneously).
Also known as afamelanotide, the half-life of Melanotan peptides is very short. It is being developed in implant form that contains control discharge effecting melanin density for dermatology use. From human lifestyle point of view, we can say that melanocortins can be one great revolution in cosmetic treatment including Botox, Viagra and much more. Although clinical trials are still going on to check the effectiveness of melanotan in bringing approved results to people. Slight effects like nausea and flushing are common after taking subcutaneous injection of melanotan. There are specific skin types and accordingly the dose of Melanotan 1 is taken to get effective and safe results.
Tuesday, February 21, 2012
Melanotan (1)
Melanotan was initially created as a way to produce a organic tan base with no exposure to the sun. The original studies understood that the best method for preventing sunburns, sun-damage and skin cancer was a healthy, pure tan base. Since there are many skin types that are more likely to burn rather than tan, the analysises started to develop this peptide in an effort to create a safe way to create pure sun safety with a sunless tan.
Later, many study has expanded to determine it’s effectiveness as a treatment for sexual dysfunctions. This analysis commenced after the original trial, conducted at the college, found that three males who were taking the peptide found that the peptide not only had quick and noticeable tanning effects, but that the side effects included spontaneous erections. They also found there was a side effect of mild nausea.
The Melanotan peptide is being studied for its ability to improve and stimulate the production of Melanin in the skin. There are many potential uses for Melanotan, but the most pervasive and explorationed use is connected to providing safe, sunless tans. added researched effects also reveal that Melanotan can act as an aphrodisiac.
This distinct peptide generally works in starting a sunless tan by binding to the melanocortin receptors. This binding process causes responses that can impact pigmentation and sexual function. This process has also been shown in some studies, to effect energy and appetite.
Studies also indicate that the tanning effects that are potentially achievable via Melanotan can do more than realize cosmetic benefits. Individuals who are identified to burn easy or who have very fair skin can reduce the change of sun connected skin problems as the darker pigmentation of their skin helps shield from sun damage and skin cancer.
This versatile peptide is also being investigated for its effects on energy, appetite and libido. Earlier study has shown optimistic affect in all three regions and studies suggest it might provide benefits for athletes or individuals who are looking to increase their workout and health.
Monday, February 20, 2012
Melanotan II
Melanotan II was developed by researchers at the University
of Arizona College of Medicine. Melanotan II is an analog of the peptide
hormone alpha-melanocyte stimulating hormone (MSH), this hormone provides a
therapeutic tan with the ability to lower the risk of skin cancer, melanocyte
stimulating hormone also plays an important role in regulating sexual arousal
in men and women.
Melanotan II has the additional effect of decreasing body fat
mass. Melanotan II It is a cyclic lactyam analog of melanocyte stimulating
hormone with the amino acid sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2.
Melanotan II is in a class of peptide hormone known as
Melanocortins (MCs). Melanocortins (MCs) are multifunctional peptide hormones
that regulate a diversity of physiological functions. Melanocortins (MCs) have
been implicated in sexual function in animals.
A Melanocortins (MCs) analog, Melanotan II, can enhance
sexual function in human males (erectile activity) and females (increased
levels of sexual desire and genital arousal). Unlike other sexual-enhancement
drugs, Melanotan II works at the level of the brain, thus eliciting a rather
natural sexual response with minimal or no undesirable side effects. The
actions of the peptide were discovered accidentally while studying the effects
of the peptide and related analogs on human skin pigmentation (tanning). (Hadley
ME, 2005).
Sunday, February 19, 2012
Sermorelin (2)
Things to consider before using Sermorelin Acetate
Some medical conditions may interact with Sermorelin Acetate. Tell your doctor or pharmacist if you have any of the following medical conditions:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to sermorelin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pregnancy
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
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