Secratatropin ingredients 3

Another ingredient contained in Secratatropin is L-Arginine. Arginine was first isolated from a lupin seedling extract in 1886 by the Swiss chemist Ernst Schultze.

Arginine is an α-amino acid. The L-form is one of the 20 most common natural amino acids. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.

Preterm infants are unable to synthesize or create arginine internally, making the amino acid nutritionally essential for them. There are some conditions that put an increased demand on the body for the synthesis of L-arginine, including surgical or other trauma, sepsis and burns.

Arginine is a conditionally nonessential amino acid, meaning most of the time it can be manufactured by the human body, and does not need to be obtained directly through the diet. The biosynthetic pathway however does not produce sufficient arginine, and some must still be consumed through diet. Individuals who have poor nutrition or certain physical conditions may be advised to increase their intake of foods containing arginine.

Necessary for the production of protein, L-arginine also helps rid the body of ammonia (a waste product) and stimulates the release of insulin. In addition, L-arginine is used to make nitric oxide (a compound that relaxes the blood vessels). Although some studies suggest that L-arginine may benefit certain health conditions, other research shows that L-arginine may have harmful effects on some individuals.

Oxytocin (3)

Scientists have discovered that the hormone oxytocin could help wallflowers overcome awkwardness in social situations
The chemical dubbed "the hormone of love" is known to increase empathy and bonding – especially parents and their children.
But now researchers have found it improves the social skills of the shy – but has little effect on those who are naturally confident.
The finding could have implications for those with severe social deficiencies, often apparent in conditions like autism.
Researchers at Israel's Seaver Autism Center for Research and Treatment and Columbia University were examining whether the hormone, which occurs naturally in the body could make us more understanding of others.

The scientists, whose research is published in Psychological Science, also measured the participants' social competency, using a test known as AQ which is usually used in autistic patients.
They found that oxytocin did improve powers of empathy – but only among those who were less socially proficient in the first place.
The more socially comfortable participants performed well on the empathetic task regardless of whether they were on oxytocin or placebo.
But less socially proficient participants performed significantly better on oxytocin, with their empathetic powers performance identical to that of the more outgoing participants.
(Richard Alleyne, http://www.telegraph.co.uk)

What should I discuss with my healthcare provider before using oxytocin?

Oxytocin (2)

How to increase Oxytocin levels
Ingestion of food triggers oxytocin release by activation of vagal afferent nerves. Most likely, it can also be released by stimulation of other senses such as olfaction, as well as by certain types of sound and light. In addition, purely psychological mechanisms can trigger the release of oxytocin. This means that positive interaction involving touch and psychological support may be health-promoting.

Oxytocin and sex
Also known as the "cuddle" hormone, oxytocin is released by both men and women at sexual orgasm.

Massage
Oxytocin can be released by various types of sensory stimulation, for example by touch and warmth. Bloodstream levels of oxytocin have been shown to rise during massage.

How it works
Oxytocin suppresses the activity of the brain region known as the amygdala, the area that processes fear and communicates it to the rest of the brain. A small sample group of 15 men inhaled either oxytocin or a placebo before performing a task in which they sorted pictures of angry or fearful faces and threatening scenes. During the test, the researchers monitored the subjects' brain activity with functional magnetic resonance imaging and found that the oxytocin group indeed had reduced activity in the amygdala.

Oxytocin (1)

Oxytocin was discovered by a British pharmacologist named Henry Dale in 1909. It was first synthesised in 1953 by Vincent de Vigneaud, an American chemist who was awarded the 1955 Nobel Prize for Chemistry for this discovery, the first polypeptide hormone to be synthesised. He also synthesised the related hormone vasopressin, which controls the body's retention of water. Oxytocin is cys-tyr-ile-gln-asn-cys-pro-leu-glu, vasopressin is cys-tyr-phe-gln-asn-cys-pro-arg-glu.

Oxytocin (Greek, “quick birth”) is a mammalian hormone that also acts as a neurotransmitter in the brain.

In humans, oxytocin is thought to be released during hugging, touching, and orgasm in both sexes. In the brain, oxytocin is involved in social recognition and bonding, and may be involved in the formation of trust between people and generosity.

In women, it is released in large amounts after distension of the cervix and vagina during labor, and after stimulation of the nipples, facilitating birth and breastfeeding, respectively. Synthetic oxytocin is sold as medication under the trade names Pitocin and Syntocinon as well as generic oxytocin.


(excerpts of) Oxytocin hormone benefits and side effects by Ray Sahelian, M.D.

Oxytocin is a hormone that helps relax and reduce blood pressure and cortisol levels. Oxytocin increases pain thresholds, has anti anxiety effects, and stimulates various types of positive social interaction. In addition, it promotes growth and healing.

Bremelanotide (PT-141)

Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II). PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.


PT-141 is the only synthetic aphrodisiac. Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike Viagra and other related medications (PDE5s), PT-141 does not act upon the vascular system, but directly through the nervous system (hypothalamus) to increase desire. Viagra, Cials and Levitra are not considered aphrodisiacs as they do not have any direct effect on the libido. However, treatment with PDE5 inhibitors and PT-141 are known to have a synergistic effect.

Bremelanotide is a melanocortin peptide hormone. PT-141 binds to the melanocortin 4 receptor (MC4R) in particular in the brain. Nine out of ten volunteers experienced sexual arousal in trials. The aphrodisiac effects of Bremelanotide are in a class of its own. 

Bremelanotide, injected (subcutaneously), has a unique window of opportunity lasting six to 72 hours. In lab trials female rats exposed to PT-141 began "flirting" with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood. 

About Melanotan

Melanotan (MT) and Melanotan II (MT-II) are both analogs of the alpha-melanocyte stimulating hormone (α-MSH) which is produced within the pituitary gland. Along with other melanocortins, they are responsible for various internal human functions including skin and hair pigmentation, appetite, libido and physical sexual arousal. Whilst these effects have been observed in both sexes, it is worth noting that increases in libido and sexual function are exclusive to MT-II.

Prompted by ultraviolet (UV) exposure, α-MSH release consequently stimulates production of melanin from the melanocytes within the skin. Melanin, as I'm sure you are aware, is a brown pigment and responsible for the tanning of the skin. Simply put, more α-MSH means more melanin, resulting in greater skin pigmentation. Since bodybuilding is such an aesthetic pursuit, and with darker skin that accentuates muscularity, it's little wonder that these drugs are in such high demand.

Melanotan may refer to one of two separate peptides:

Afamelanotide, originally developed under the names "Melanotan-1" or "Melanotan I" for skin tanning, a drug currently in trials in implant form as a prophylactic treatment for a series of light affected skin disorders and potential skin cancer preventative agent

Melanotan II, a drug originally developed as a skin tanning agent, but subsequently investigated as a potential treatment for sexual dysfunction.

While Melanotan is a straight, full length peptide, Melanotan II is a shortened, circular version of the afamelanotide peptide. While both Melanotan and Melanotan II have a tanning effect, there are some more side effects reported by users of MT II. Libido enhancement and spontaneous erections are surprising side effects of MT II that have been reported by the users.

MT causes tanning without any side effects and hence it is considered to better of the two peptides. But because the amino acid sequence is shorter in MT II, there are more MT II peptide chains available as compared to MT. Another major difference between MT and MT II is that MT II is cheaper than MT and this lures people to go for it rather than MT.