Showing posts with label injection. Show all posts
Showing posts with label injection. Show all posts

Sunday, February 26, 2012

About GHRP-6 (2)




GHRP-6 stands for “growth hormone releasing peptide”. As the name suggests, the product works by stimulating the body to release more Human Growth Hormone (HGH) and IGF-1. HGH and IGF-1 levels decline rapidly as one gets older, and it is this decline which is thought to be responsible for the aging process. Besides a much lower cost, GHRP-6 offers another distinct advantage over HGH injections as it does not shut down the body’s natural production of this hormone, it just enhances it.

Compared to GHRP-2, GHRP-6 is more attractive because at the recommended dosage it does not lead to desensitization and therefore diminishing effect over time as can happen with GHRP-2.

Possible benefits: Fat loss, muscle gain, increased strength, improved skin tone, better sleep, more energy, stronger bones and connective tissues.


Useful for: Bodybuilders looking to gain muscle; Ordinary people looking to lose fat; older persons looking for anti-aging benefits.
Use it before bed and/or post workout. Taken on an empty stomach (at least 2 hours since last meal), then wait at least 20-30 minutes after your injection before eating.
Works by subcutaneous injection into fat. It can be simultaneously injected in the same syringe as other peptides.

Description:
Growth Hormone Releasing Peptide-6 Synthetic is a single, non-glycosylated polypeptide chain containing 6 amino acids, having a molecular mass of 873 Dalton and a Molecular formula of C46H56N12O6.

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Solubility:
It is recommended to reconstitute the lyophilized GHRP-6 in sterile 18MO-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Thursday, February 23, 2012

About GHRP-6 (1)




In the world of bodybuilding, GHRP-6 is useful as it facilitates enhancements in terms of normal pulsatile physiological secretion by its hypothalamic action and pulsatile secretory bursts of GH. The list of benefits also include improved natural production of growth hormone, sound sleep, sense of well being, and fast healing of joints and tendons.

GHRP-6 stands for “growth hormone releasing peptide”. As the name suggests, the product works by stimulating the body to release more Human Growth Hormone (HGH) and IGF-1. HGH and IGF-1 levels decline rapidly as one gets older, and it is this decline which is thought to be responsible for the aging process. Besides a much lower cost, GHRP-6 offers another distinct advantage over HGH injections as it does not shut down the body’s natural production of this hormone, it just enhances it. 

This peptide has a strong effect on the body's release of GH. It almost promotes hunger and appetite by stimulating a release in Ghrelin which is a peptide in the stomach which promotes appetite and gastric emptying. GHRP-6 acts by stimulating the anterior pituitary gland which causes an increased released of GH. GHRP-6 is used for a range of medical issues including low natural GH production and to promote weight gain in abnormally thin individuals.

Wednesday, February 1, 2012

CJC-1295




CJC-1295 is a long-acting GHRH analog and stimulates GH and IGF-1 secretion. It will keep a steady increase of HGH and IGF-1 with no increase in prolactin. [1] CJC-1295 represents a very exciting new compound that has the potential to increase growth hormone and IGF-I secretion and effects, with a built-in safeguard (the feedback effects of IGF-I) to limit excessive elevations of GH and IGF-1 levels. Intense fat loss. Increases protein synthesis for more muscle growth. GHRHKO animals receiving daily doses of CJC-1295 exhibited normal body weight and length. Mice treated every 48 and 72 h reached higher body weight and length than placebo-treated animals, without full growth normalization.



Sequence: Tyr-DAla-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys-(Maleimidopropionyl)-NH2

Formula: C164H266N47O46

Bremelanotide (PT-141)





Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II). PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.


PT-141 is the only synthetic aphrodisiac. Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike Viagra and other related medications (PDE5s), PT-141 does not act upon the vascular system, but directly through the nervous system (hypothalamus) to increase desire. Viagra, Cials and Levitra are not considered aphrodisiacs as they do not have any direct effect on the libido. However, treatment with PDE5 inhibitors and PT-141 are known to have a synergistic effect.

Bremelanotide is a melanocortin peptide hormone. PT-141 binds to the melanocortin 4 receptor (MC4R) in particular in the brain. Nine out of ten volunteers experienced sexual arousal in trials. The aphrodisiac effects of Bremelanotide are in a class of its own. 

Bremelanotide, injected (subcutaneously), has a unique window of opportunity lasting six to 72 hours. In lab trials female rats exposed to PT-141 began "flirting" with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood. 

How to use Melanotan?




Melanotan and Melanotan II are supplied in vials as powders that need to be mixed with bacteriostatic water for injection. The Melanotan and Melanotan II powder are best stored in a freezer due to their slow degradation at room temperature, and are often shipped in ice packs for this reason. The degrading process is slow, so if your Melanotan did not get shipped in ice packs it will not make your batch that less effective as long as the exposure to the higher temperature has not exceeded several days.
As previously stated, Melanotan needs to be mixed with bacteriostatic water prior to injection. To achieve a concentration of 10mg/8ml, use 8ml of bacteriostatic water in your 10mg vial of powder. From this we can have a concentration level of 0.25mg per 0.2ml. This should be enough liquid for you to accurately draw up using a 1ml marked syringe, although you could choose your own concentration level using a similar process. By using a 1ml syringe we can successfully attach and detach needles, and store the solution filled syringe in the fridge ready for the next injection.
The dosages of Melanotan are greater then that of Melanotan II. A daily dosage of 2-3mg of Melanotan will bring about fruitful results, and a daily dosage of 1mg will do the same for Melanotan II. To restrict the undesirable side effects it is often best to start the dosages at a level of 1-1.5mg for Melanotan and 0.25mg-0.5mg for Melanotan II, and build the dosages by .25mg each day until the target dosage is reached.

The injection itself is done into the sub-cutaneous layer.

Both MT and MT II can be used for extended periods, whereby there is an initial daily administration of perhaps 2-3 weeks or until desired level of pigmentation has been achieved, followed by a maintenance phase of two injections per week.
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