L-Arginine

Arginine (abbreviated as Arg or R) is an a-amino acid. It was first isolated in 1886. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that codify for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. Preterm infants are unable to synthesize or create arginine internally, making the amino acid nutritionally essential for them. There are some conditions that put an increased demand on the body for the synthesis of L-arginine, including surgical or other trauma, sepsis and burns.[citation needed] Arginine was first isolated from a lupin seedling extract in 1886 by the Swiss chemist Ernst Schultze.

In general, most people do not need to take arginine supplements because the body usually produces enough. The amino acid side-chain of arginine consists of a 3-carbon aliphatic straight chain, the distal end of which is capped by a complex guanidinium group.
Delocalization of charge in guanidinium group of L-Arginine

With a pKa of 12.48, the guanidinium group is positively charged in neutral, acidic and even most basic environments, and thus imparts basic chemical properties to arginine. Because of the conjugation between the double bond and the nitrogen lone pairs, the positive charge is delocalized, enabling the formation of multiple H-bonds.

The Function of Alanine

Alanine is an amino acid that classified as non-essential amino acid. It can be developed into glucose in amino cycle because it is part of the glucogenic amino acid. The molecular structure of the alanine is simple Alanine is available in food. Meat, egg, gelatin, fish, milk, and dairy products are the example of the alanine from animal sources. Besides that, it is also able to be got in plant. Alanine can be got from rice, soy, nuts, corn, seeds, etc.

The synthesis of the alanine is not too complicated. Alanine is part of the manufacture of the human body. Alanine consists of many types of amino acid. From that, reaction can be made in the form of transamination. Transamination is a transfer from one amino acid to another. Then, it can create new amino acid. Alanine is made in the muscle from the reaction of glutamic acid and pyruvic acid.

Alanine an Amino Acid

Alanine, or L-alanine, is an amino acid that helps the body convert the simple sugar glucose into energy and eliminate excess toxins from the liver. Amino acids are the building blocks of protein, and are key to building strong, healthy muscles-alanine has been shown to help protect cells through being harmed in the course of intensive exercise task, if your human body cannibalizes muscles protein to aid generate energy.

Alanine is crucial for preserving balanced levels of nitrogen and glucose in the body, which it does through a series of chemical actions called the alanine cycle. During the alanine cycle, any excess amino acids (proteins) in cells or tissues are transferred to a receptor molecule called pyruvate, which is produced by the breakdown of glucose. The pyruvate is then converted to alanine and transferred to the liver. The liver extracts nitrogen from alanine and converts some of it back into pyruvate, which can then be used to produce more glucose. Any excess nitrogen is then converted into urea and passed out of the body during urination. This cycle, glucose-pyruvate-alanine-pyruvate-glucose, helps supply the body with the energy it needs to support cellular life. It also ensures that a constant supply of pyruvate is available to allow the synthesis of glucose and amino acids in the body.

Alanine is a nonpolar amino acid with an aliphatic R group (-CH3), therefore it does not easily dissolve in water. Amino acids for polymers that make up proteins which carry out many of required functions of a cell. An aliphatic R group means that the substituent is not aromatic but rather has a carbon based chain like an alkane. The side chain of Alanine tends to cluster together within proteins which in turn stabilize the internal structure of the protein by means of hydrophobic interactions. The hydrophobic interactions give the protein more stability and help to dictate secondary, tertiary and quaternary structure. This methyl group makes Alanine one of the more simple amino acids from a molecular pint of view. The methyl group is rarely directly involved in enzymatic reactions. Like all twenty of the common amino acids, the ?-carbon is attached to the methyl substituent as well as the amino and carboxyl groups of the main backbone of the amino acid. Alanine is also ambivalent, meaning that it can be found both inside and outside of the protein.
Alanine can be abbreviated with the three letter combination of Ala or with the single letter A. The chemical formula is CH3CH(NH2)COOH. It is a nonessential amino acid and is directly produced by the body. It is also required for metabolism of glucose, a simple carbohydrate that the body uses for energy, and tryptophan in the body. Alanine is a plays a key role in important source of energy for the muscle tissue, brain and central nervous system. It also helps to produce antibodies for the immune system. Alanine plays a major role in the transfer of nitrogen from peripheral tissue to the liver in the glucose-alanine cycle.

What Are the Benefits of Glutamic Acid

Glutamic acid is a common amino acid and considered nonessential because it can be synthesized in the body, specifically in your brain where by it functions because a neurotransmitter, or chemical messenger. As such, glutamic acid is considered "brain fuel" and important for increased head functions. It is also important for muscle function, specifically progress along with reduced recovery time. Further, glutamic acid is needed to remove toxic ammonia from the brain and muscles. By interacting with ammonia, glutamic acid converts into glutamine and becomes a powerful antioxidant.

Brain Functions
As a neurotransmitter, glutamic acid appears to support mental functioning, including boosting IQ, enhancing alertness, balancing mood and preventing senility. Glutamic acid is also needed, along with vitamin B6 and manganese, to form GABA, another important neurotransmitter. One of the first studies on glutamic acid in 1952 found that mentally challenged teenage boys who were given glutamic acid for 10 months responded well and almost half increased their IQ scores by up to 11 points. A Boston University study published in a 2010 edition of "Experimental Neurology" found that people with Parkinson's disease have significantly lower levels of glutamic acid in their Glutamic acid may also play roles in schizophrenia, depression, addiction and alcoholism.

Muscle Functions
Glutamic acid is of particular interest to athletes, especially bodybuilders, because it is involved in the regeneration and recovery of damaged muscle cells following periods of intensive exertion. Over 60 percent of the amino acids found within skeletal muscle is L-glutamine, which is derived from glutamic acid's catabolism of ammonia. L-glutamine is needed for protein metabolism, which is essential for muscle repair and growth. Further, glutamic acid is an intermediary in cellular metabolism and energy production, which is why it helps reduce fatigue. Due to its effect on muscle cells, glutamic acid may prove effective in the treatment of muscular dystrophy and other muscle wasting conditions.
Other Benefits

Benefits of L-Valine: Improved Cognitive Function

The benefits of valine were not known to the medical world until its discovery in 1901. A German Scientist by name Emil Fischer was the first to discover L-valine in the course of his research. Since then the medical world has paid attention to this essential amino acid. L-valine is one of the three branched-chain amino acids popular abbreviated as (BCAAs). This amino acid plays important role in the body such as improvement of the cognitive power, stress management and energy and muscle metabolism.

In the bio-medical and pharmaceutical parlance, essential nutrients are those nutrients required for the proper functioning of the body which are not produced by the body itself. The body gets this through supplements and other means like pills, capsules and injections. With regard to L-valine, the body cannot produce it. It is one of those amino acids that are received outside the body. There are certain food sources through which L-valine is received. Such food sources include: soy flour, fish, grains, mushrooms, peanuts, cottage cheese, vegetables, meat and others. Given the benefits of valine there are some supplements available today through which L-valine can be obtained.

One of the benefits of valine is the improvement of cognitive power. Traumatic brain injury can lead to some neurological dysfunction which can to cause the impairment of cognition. When such a situation occurs, the consumption of L-valine (BCAAS) will be one of the best treatment options in order to remedy the situation. These dietary supplements can resuscitate and reverse the injury-induced shifts in net synaptic. This in turn brings the cognitive power to normal. Experiment was carried out in this regard with mice. It was discovered that all mice with a brain injury that ate L-valine and other supplements made of other BCAAS improved in their cognitive performance. Some individuals believe that this proves beyond reasonable doubt that l-Valine supplement can be used to improve cognitive performance.

GABA

A number of anti-wrinkle creams out there contain GABA. Is that a good thing? Is GABA really an essential ingredient in anti-aging creams? Or is it something that just adds to the cost of the product?

GABA is short for gamma amino butyric acid, a non-essential amino acid that naturally occurs in the body and serves to inhibit, rather than excite or stimulate, responses. Because of its relaxant properties,

GABA is effective in:
•    treating anxiety and sleep disorders
•    enhancing mood
•    the secretion of the human growth hormone (HGH)
•    calming the nervous system

Glycine

Glycine is just about the non-essential proteins which are utilized to help develop muscle tissue and also transform sugar in electricity. It is also vital to sustaining balanced key worried along with intestinal programs, and contains been shown to shield you via antioxidants through some kinds of cancer malignancy.

 

Glycine is needed within the body to assist develop standard Geonomics as well as RNA strands-the innate substance necessary for right cell purpose and configuration. It will help steer clear of the breakdown of muscle simply by boosting the particular body’s numbers of creatine, a compound that assists create muscles. High concentrations of mit regarding glycine tend to be found not just in this muscle tissues, in skin along with other connective tissues too. Nearly 1/3 connected with collagen, which keeps your skin layer as well as ligament agency and flexible, includes glycine. (Large degrees of Glycine will also be found in gelatin, the industry type of denatured bovine collagen). Without glycine your body would not be in a position to mend damaged tissues; skin would become slack the way it fell for Ultra violet rays, oxidation, and also molecular harm, and chronic wounds would not recover.

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Last but not least, the final ingredient of Secratatropin, L-Ornithine.

L-ornithine is a non-protein amino acid, meaning that it is synthesized from protein molecules in the body. This amino acids which are often used by bodybuilders and those in the fitness industry to improve how their bodies produce muscle.

L-ornithine is mostly used because it helps the body to produce HGH which will lead to increased muscle size and strength. This amino acid is also helpful in wound healing and collagen production because of the detoxification properties it encourages and the increased protein synthesis. L-Ornithine is most often combined with Arginine for their synergistic properties.

L-Ornithine is also used to assist in liver and gallbladder cleansing because it helps to produce urea that is used to flush toxic substances out of the liver. Because of the detoxification properties of the amino acid it is thought to decrease the incidence of gallstones and liver toxins.
(L-ornithine Side Effects | eHow.com http://www.ehow.com/about_5047324_lornithine-side-effects.html#ixzz1qUe9vNjm)

Ornithine is an amino acid found in fish, meat, eggs, and dairy, but the body also produces it when arginine is metabolized, producing urea.

Benefits
- elevating the growth hormone levels
- vital in the anti-aging process
- help the body to recover fast from trauma, burns, infections and even cancer
- increases insulin
- build and maintain muscles during intensive physical training
- helps deal with muscle loss that happens during the aging process
- Surgical or traumatic injury increases the body’s need for L-Ornithine to repair damaged tissue and bone.

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Let's learn more about one of Secratatropin's ingredients, which is L-Leucine.


L-Leucine is an essential amino acid, is known as one of three branch-chain amino acids, which means that the body doesn’t produce it naturally. So for the body to get this key amino acid in the system it has to pull them from a variety of foods, but some--especially vegetarians--can benefit from dietary supplements. Amino acids are the building blocks from which proteins are made, and leucine is a component of femtin and astacin, two "buffer" proteins. The chemical formula of leucine is HO2CCH(NH2)CH2CH(CH3)2, and it is classified as a hydrophobic, meaning water-insoluble, protein.
(Read more: http://www.livestrong.com/article/263493-definition-of-leucine/#ixzz1qTSR1SGj)

Dietary Source
Leucine is found in foods that are high in protein, such as fish, meats, poultry and cottage cheese, as well as brown rice, beans, nuts and whole wheat.Foods high in leucine and protein can help maintain muscle while attempting to reduce body fat during weight loss.

A single 4 oz. serving of meat or poultry could supply a 130lb person with up to144 percent of the daily recommended intake of leucine. Seeds and nuts contain less leucine than meat, poultry and seafood; however, they are still high in the essential amino acid. Dairy (products) is another good source of leucine.

Dosage
Your requirements for leucine will depend on your weight, but an intake of 5 grams of leucine, in combination with 4 grams of valine, and 2 grams of isoleucine per day, may be healthy. People who are active may use leucine, in combination with valine and isoleucine, to help increase muscle gains.These needs can be met by adding whey protein powder to your diet. Talk to your doctor if you think you need to supplement your diet with leucine or if adding a leucine-rich whey protein product to your diet may help you gain and maintain muscle and energy.

Eat a low carbohydrate diet while taking leucine to prevent muscle breakdown and to maintain high energy levels. A protein rich diet further helps to increase muscle growth while taking leucine supplements. Individuals with kidney or liver function problems should not take leucine without first consulting a doctor, as ingesting large doses of amino acids may worsen these disorders.
(Read more: http://www.livestrong.com/article/394679-how-to-take-leucine/#ixzz1qTRnyNAO)

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L-Lysine is listed as one of Secratatropin's ingredient.

Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. It is an essential amino acid, which means that the human body cannot synthesize it.

Dietary sources
Good sources of lysine are foods rich in protein such as soy, as well as meat (specifically red meat, lamb, pork, and poultry), cheese (particularly Parmesan), certain fish (such as cod and sardines), and eggs.

Lysine is the limiting amino acid (the essential amino acid found in the smallest quantity in the particular foodstuff) in most cereal grains, but is plentiful in most pulses (legumes). Consequently, meals that combine cereal grains and legumes, such as the Indian dal with rice, Middle Eastern hummus, ful medames, falafel with pita bread, the Mexican beans with rice or tortilla have arisen to provide complete protein in diets that are, by choice or by necessity, vegetarian. A food is considered to have sufficient lysine if it has at least 51 mg of lysine per gram of protein (so that the protein is 5.1% lysine).

L-Lysine Benefits: Functions & Benefits of L-Lysine
- L-Lysine natural help for shingles exists. Shingles lesions are painful due to reactivation of the varicella-zoster virus. L-Lysine appears to help treat the eruption of shingles. However, there still needs to be more research conducted to definitively proclaim it a major factor. Many have used steroids an antiviral drugs as well. Herbalists say it is helpful as well.

- L-Lysine benefits include reducing the severity of herpes-related cold sores. L-Lysine inhibits the herpes virus. It prevents and relieves cold sores around genital areas, which are type 2 herpes as well as helping type 1 herpes, which is not as harsh as type 2.

- Benefits of L-Lysine also include a role in promoting good bone health
As L-Lysine is necessary for collagen synthesis, it has a role to play in healthy skin, ligaments, and tendons.

Lysine helps the body absorb calcium and decreases the amount of calcium that is lost in urine. Because calcium is crucial for bone health, some researchers think lysine may help prevent bone loss associated with osteoporosis. Lab studies suggest that lysine in combination with L-arginine (another amino acid) makes bone building cells more active and enhances production of collagen. But no studies have examined whether lysine helps prevent osteoporosis in humans.
(Read more: http://www.umm.edu/altmed/articles/lysine-000312.htm#ixzz1qBzYRI3h)

- When taken with vitamin C, l-lysine appears to help symptoms of the heart condition angina pectoris.

- Also, since low levels of l-lysine have been associated with depression, chronic viral infections, asthma, and low levels of thyroid hormones, there are possible l-lysine benefits for people with those conditions as well.

- Further, l-lysine appears to work with equal amounts of the amino acid arginine to build muscle.

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L-Valine is included as Secratatropin's ingredients.

Valine (abbreviated as Val or V)[3] is an α-amino acid with the chemical formula HO2CCH(NH2)CH(CH3)2.  L-Valine is not processed by the liver, it is taken up by muscles.

L-Valine is one of 20 proteinogenic amino acids.
Valine is an essential amino acid, hence it must be ingested, usually as a component of proteins. Amino acids are essential for everyday body functions, as well as for maintaining muscle and regulation of the immune system. It is synthesized in plants via several steps starting from pyruvic acid. The initial part of the pathway also leads to leucine.

Human dietary sources include cottage cheese, fish, poultry, peanuts, sesame seeds, and lentils. L-Valine is suitable for vegetarians.

L-Valine is necessary for smooth nervous system and cognitive functioning. It is one of the three Branched Chain Amino Acids (BCAAs), the other two being L-leucine and L-isoleucine.

Valine is commonly used by bodybuilders, in conjunction with isoleucine and leucine to promote muscle growth. It also provides energy and helps to repair tissues that are damaged during physical activity.
It increases cognitive function and smooths nervous system functioning. L-Valine assists in maintaining proper nitrogen balance in the human body.

Valine is necessary for muscle metabolism and growth of muscle tissue. It also helps to maintain the proper amount of nitrogen in the body. Because it is a branched-chain amino acid, Valine can be used as an energy source in your muscles, preserving the use of glucose.

Because Valine is so essential for preserving, repairing and building muscle tissue, it is recommended for people involved with bodybuilding and other sports that require excessive use of the muscles.

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Secratatropin contains so many natural substances, including L-Tyrosine.

Tyrosine (abbreviated as Tyr or Y)[1] or 4-hydroxyphenylalanine, is one of the 22 amino acids that are used by cells to synthesize proteins.
The word "tyrosine" is from the Greek tyri, meaning cheese, as it was first discovered in 1846 by German chemist Justus von Liebig in the protein casein from cheese. It is called tyrosyl when referred to as a functional group or side chain.

It plays an important role in the production of neurotransmitters that regulate emotions. The body makes l-tyrosine from another amino acid, known as phenylalanine.


Dietary sources
Tyrosine, which can also be synthesized in the body from phenylalanine, is found in many high-protein food products such as:
- soy products
- chicken
- turkey
- fish
- peanuts
- almonds
- avocados
- milk
- cheese
- yogurt
- cottage cheese
- lima beans
- pumpkin seeds
- and sesame seeds.
Tyrosine can also be obtained through supplementation.

People take tyrosine for:
- depression
- attention deficit disorder (ADD)
- attention deficit-hyperactivity disorder (ADHD)
- the inability to stay awake (narcolepsy)
- improving alertness following sleep deprivation.
- It is also used for stress, premenstrual syndrome (PMS), Parkinson's disease, Alzheimer's disease, chronic fatigue syndrome (CFS), alcohol and cocaine withdrawal, heart disease and stroke, ED (erectile dysfunction), loss of interest in sex, schizophrenia, and as a suntan agent and appetite suppressant.
- Some people also apply tyrosine to the skin to reduce age-related wrinkles.
- libido enhancement

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Secratatropin contains many beneficial substances, including L-Isoleucine.


What is L-Isoleucine?
L-Isoleucine is a branch chain amino acid (BCAA) and is one of three BCAAs, the other two being L-leucine and L-valine. It is an essential amino acid, which means it must come from ingestion (food or supplements), Some of these foods include  include eggs, cashews, almonds, fish, chicken, soybeans, chickpeas, lentils, liver, milk, cottage cheese and cereal grains. L-Isoleucine is crucial in the production of hemoglobin. It also regulates blood sugar levels as well as energy levels. It is metabolized in muscle tissue and is responsible for muscle recovery after exercise.

For athletes or anyone who practices regular strenuous physical activity, IsoLeucine supplements are recommended. Although there are foods that contain this amino acid, people who are extremely active and exercise heavily need more IsoLeucine in their bodies to repair and protect muscle tissues.
IsoLeucine is probably best known for its use in increasing endurance and helping heal and repair muscle tissue. Serious athletes and bodybuilders need this amino acid because of its ability to boost energy levels and help the muscles recover from strenuous exercise and other physical activities.

Bodybuilding requires energy and endurance. By using IsoLeucine along with Valine and Leucine, the muscles fully recover after exercise. IsoLeucine is literally broken down within the muscle tissue to provide energy.

What are the benefits of L-Isoleucine?
- Used for fuel, along with L-leucine and L-valine
- Helps muscle recovery
- Speeds wound healing
- Promotes the growth of new tissue
- Increases the bio-availability of complex carbohydrate intake
- Promotes anabolic muscle building
- Helps neurotransmission

Secratatropin Ingredients 5

L-Glutamine is also one of Secratatropin's ingredients.

L glutamine is the most abundant amino acid found in human muscle and plasma. Over 60% of the free-floating amino acid pool in skeletal muscle cells is made up of L glutamine. Glutamine is unique in that like glucose it is one of the preferred energy sources utilized by rapidly proliferating cells. It is a major fuel source for the brain and together with its relatives the stimulant neurotransmitter Glutamic acid and the inhibitory neurotransmitter GABA they form the most abundant amino group in the human brain.

It is also a primary nitrogen donor, meaning that it moves the nitrogen around in the body to where it is needed. Maintaining a positive nitrogen balance is absolutely necessary for muscle building.

It is released from the muscle during times of stress (such as hard weight training workouts) and dieting. This amino acid not only has been shown to be a great anti-catabolic agent (protects the muscle from the catabolic activities of the hormone cortisol), to be a contributor to muscle cell volume, and to have immune system enhancing properties but also to help in the following ways:

- Regulation of protein synthesis (this is one of the ways in which steroids exert their muscle building effects).
- Accelerating glycogen synthesis after a workout.
- Sparing the use of the glycogen stored in the muscle cell (recall that the glycogen stored in the muscle cell is what gives the cell the healthy volume and firmness that you seek).
- Faster recuperation from weight training workouts.

Natural sources of L-glutamine include beef, chicken, fish, eggs, milk, dairy products, wheat, cabbage, beets, beans, spinach, and parsley. Small amounts of free L-glutamine are also found in vegetable juices.

Secratatropin's Ingredients 4

L-Dopa is one of Secratatropin's ingredients.

L-Dopa is an amino acid that converts into dopamine. Dopamine is an essential component of our body and it’s required for proper functioning of the brain. Research discovered the body converts the amino acid tyrosine into L-dopa; L-dopa is then converted into dopamine. Without the neurotransmitter dopamine to serve a damping effect on neural transmissions, muscles become tense and tremble.

L- Dopa contains natural secretagogues which may support the body’s ability to stimulate the natural release of growth hormone. The blood carries the dopamine into the brain, where it naturally increases HGH production from the pituitary gland. The increased dopamine levels also optimize the production of other hormones, including testosterone, leading to increased sex drive and improved sexual performance for both men and women,  beneficial in stimulating muscle growth, as well as burning fat from fat cells.

L-DOPA (L-3,4-dihydroxyphenylalanine) is a chemical that is made and used as part of the normal biology of some animals and plants. Some animals including humans make it via biosynthesis from the amino acid L-tyrosine. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) collectively known as catecholamines. L-DOPA can be manufactured and in its pure form is sold as a psychoactive drug with the INN levodopa; trade names include Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, etc.). As a drug it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia

In work that earned him a Nobel Prize in 2000, Swedish scientist Arvid Carlsson first showed in the 1950s that administering L-DOPA to animals with Parkinsonian symptoms would cause a reduction in their intensity. This treatment was later extended to manganese poisoning and later Parkinsonism by George Cotzias and his coworkers, who greatly increased the dose. The neurologist Oliver Sacks describes this treatment in human patients with encephalitis lethargica in his book Awakenings, upon which the movie of the same name is based.

Secratatropin ingredients 3

Another ingredient contained in Secratatropin is L-Arginine. Arginine was first isolated from a lupin seedling extract in 1886 by the Swiss chemist Ernst Schultze.

Arginine is an α-amino acid. The L-form is one of the 20 most common natural amino acids. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.

Preterm infants are unable to synthesize or create arginine internally, making the amino acid nutritionally essential for them. There are some conditions that put an increased demand on the body for the synthesis of L-arginine, including surgical or other trauma, sepsis and burns.

Arginine is a conditionally nonessential amino acid, meaning most of the time it can be manufactured by the human body, and does not need to be obtained directly through the diet. The biosynthetic pathway however does not produce sufficient arginine, and some must still be consumed through diet. Individuals who have poor nutrition or certain physical conditions may be advised to increase their intake of foods containing arginine.

Necessary for the production of protein, L-arginine also helps rid the body of ammonia (a waste product) and stimulates the release of insulin. In addition, L-arginine is used to make nitric oxide (a compound that relaxes the blood vessels). Although some studies suggest that L-arginine may benefit certain health conditions, other research shows that L-arginine may have harmful effects on some individuals.

Secratatropin's ingredients 2

One of Secratatropin's ingredients is GABA.

Gaba is a unique amino acid that acts as a neurotransmitter in the central nervous system. When used correctly, GBAB may be able to raise HGH levels in the bloodstream and even improve the body’s sleep cycle (allowing for a deeper, more restful sleep). Although its abilities are still being studied, Gaba has not resulted in any long-term or negative side-effects.


It is also used for brain metabolism and to treat both epilepsy and hypertension where it is thought to induce tranquility in individuals who have a high activity of manic behavior and acute agitation.

Gamma-Aminobutyric Acid can be used to calm a person, much like tranquilizers, but without the possibility of addiction.

It is sometimes used as sexual a stimulant because of its relaxing capabilities, as well as with prostate problems, since it also assists with the release of sex hormones.

Symptoms of GABA deficiency
Normally, the brain produces all the GABA we need. Unfortunately, due to a poor diet, exposure to environmental toxins, or other factors, levels of GABA may become depleted and so many people may be deficient without even realising it.
Main symptoms of GABA deficiency include:
- anxiety
- irritability
- insomnia
- depression
- palpitations

Benefits of GABA
- Promote better sleep
GABA promotes relaxation and induces better sleep by easing anxiety.

- Epilepsy
A link has been made to low GABA levels and epileptic seizures in some patients - in these cases, extra GABA appeared to inhibit nerve cells in the brain from firing and setting off seizures.

- Chronic pain
Stress can aggravate pain, making it feel worse. As a natural stress-reducer, GABA supplements can help to relieve the intensity of pain and as it reduces the pain-related nerve impulses to make the sensation of feeling pain a lesser experience.

-ADHD
GABA is effective in treating attention deficit hyperactivity disorder (ADHD).

Secratatropin's ingredients 1

The formula for Secratatropin HGH is composed mostly of amino acids. Some of these amino acids are present to induce increased HGH production in the system while others are needed to maintain proper cell function and muscle growth. The list includes:
- Alpha GPC
- GABA
- L-Arginine
- L-Dopa
- L-Glutamine
- L-Isoleucine
- L-Tyrosine
- L-Valine
- L-Lysine
- L-Leucine
- L-Ornithine

Alpha GPC
L-Alpha Glycerylphosphorylcholine (Alpha GPC, choline alfoscerate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have potential for the treatment of Alzheimer's disease and is used as a nootropic dietary supplement to enhance memory and cognition.

Alpha GPC rapidly delivers choline to the brain across the blood-brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter. Alpha GPC is derived from highly purified soy lecithin.
The current understanding of Alpha-GPC's actions in the brain is that it increases hGH secretion in the pituitary by two separate but interacting neuro-endocrine mechanisms; these are:

1. Modulatory - increasing cholinergic tone lending to decreased levels of somatostatin (produced by the hypothalamus), as a result of the administration of Alpha-GPC;

2. Regulatory - stimulation of hGH synthesis resulting from 'up regulation' of Growth Hormone Releasing Hormone/Factor (GHRH/GHRF) in conjunction with receptor-linked stimulation of the adenylate cyclase (cAMP)-Protein kinase C (PKC)-inositol triphosphate (IP3) intracellular control mechanisms regulating hGH synthesis at the genomic level and its subsequent secretion by the anterior pituitary.

About Human Growth Hormone

Growth hormone is a powerful anabolic hormone that occurs naturally in the human body. It is produced by the pituitary gland in the brain and stimulates the growth of muscle, cartilage, and bone. It is made throughout a person's lifetime but is more plentiful during youth. It stimulates growth in children and plays an important role in adult metabolism.

Aging is very much related to what we call Human Growth Hormone (HGH). It is a complex hormone that houses 191 amino acids and it is being produced chiefly by the pituitary gland.

HGH has been used since the 1950s to help children with growth problems, but it stayed under the radar for other uses until 1990, when Dr. Daniel Rudman reported in the New England Journal of Medicine that men taking a six-month course of HGH reduced their body fat by 14.4 percent while increasing lean muscle mass by 8.8 percent.
The study included just a dozen men, but it inspired a flood of anti-aging literature touting the benefits of growth hormone, along with countless web sites selling HGH creams and sprays.
(Human growth hormone use rises, but is it legal? April 11, 2007 By Caleb Hellerman CNN)

Since HGH is related to several body parts and functions, enhancement or increase of the HGH will be of big help. There are several benefits of HGH enhancement and one of these benefits is an increase in the level of energy. As we get older, a decrease in the energy level will be encountered. There are physical activities that we will not be able to accomplish anymore due to the lowering of energy.

About CJC-1295

CJC-1295 was developed for clinical trials in the year 2000. The drug was originally synthesized to remove visceral fat deposits in AIDS patients. CJC 1295 was ultimately successful on all research subjects, as increasing the level of growth hormone in the body proved to increase fat loss.

Various experiments have been conducted to test the effectiveness of CJC-1295 in vivo and the Journal of Clinical Endocrinology & Metabolism has reported dose-dependent increases in mean plasma GH concentrations by 2-10 fold for more than 6 days and increased IGF-1 concentrations 1.5-3 fold for 9-11 days after a single injection.

Not only that but they proved the mean half life to be 5.8-8.1 days and after multiple doses showed mean IGF-1 levels remained above baseline for up to 28 days following! No serious adverse reactions were reported in any group.

Another very positive benefit of CJC-1295/CJC-1293 is its ability to promote slow wave sleep. Slow wave sleep is also known as deep sleep and is the portion of sleep responsible for the highest level of muscle growth and memory retention. SWS are decreased significantly in older adults and also with people who tend to exercise later in the evening.

About GHRP-6 (2)

GHRP-6 stands for “growth hormone releasing peptide”. As the name suggests, the product works by stimulating the body to release more Human Growth Hormone (HGH) and IGF-1. HGH and IGF-1 levels decline rapidly as one gets older, and it is this decline which is thought to be responsible for the aging process. Besides a much lower cost, GHRP-6 offers another distinct advantage over HGH injections as it does not shut down the body’s natural production of this hormone, it just enhances it.

Compared to GHRP-2, GHRP-6 is more attractive because at the recommended dosage it does not lead to desensitization and therefore diminishing effect over time as can happen with GHRP-2.

Possible benefits: Fat loss, muscle gain, increased strength, improved skin tone, better sleep, more energy, stronger bones and connective tissues.


Useful for: Bodybuilders looking to gain muscle; Ordinary people looking to lose fat; older persons looking for anti-aging benefits.
Use it before bed and/or post workout. Taken on an empty stomach (at least 2 hours since last meal), then wait at least 20-30 minutes after your injection before eating.
Works by subcutaneous injection into fat. It can be simultaneously injected in the same syringe as other peptides.

Description:
Growth Hormone Releasing Peptide-6 Synthetic is a single, non-glycosylated polypeptide chain containing 6 amino acids, having a molecular mass of 873 Dalton and a Molecular formula of C46H56N12O6.

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Solubility:
It is recommended to reconstitute the lyophilized GHRP-6 in sterile 18MO-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

About GHRP-6 (1)

In the world of bodybuilding, GHRP-6 is useful as it facilitates enhancements in terms of normal pulsatile physiological secretion by its hypothalamic action and pulsatile secretory bursts of GH. The list of benefits also include improved natural production of growth hormone, sound sleep, sense of well being, and fast healing of joints and tendons.

GHRP-6 stands for “growth hormone releasing peptide”. As the name suggests, the product works by stimulating the body to release more Human Growth Hormone (HGH) and IGF-1. HGH and IGF-1 levels decline rapidly as one gets older, and it is this decline which is thought to be responsible for the aging process. Besides a much lower cost, GHRP-6 offers another distinct advantage over HGH injections as it does not shut down the body’s natural production of this hormone, it just enhances it. 

This peptide has a strong effect on the body's release of GH. It almost promotes hunger and appetite by stimulating a release in Ghrelin which is a peptide in the stomach which promotes appetite and gastric emptying. GHRP-6 acts by stimulating the anterior pituitary gland which causes an increased released of GH. GHRP-6 is used for a range of medical issues including low natural GH production and to promote weight gain in abnormally thin individuals.

Melanotan (2)

To get a visibly flawless skin, you must know about this peptide as how it can provide you an exquisitely beautiful skin. Melanotan 1 is basically a synthetic derivative of its own natural counterpart called alpha-melanocyte-stimulating hormone (a-MSH).

The presence of two amino acids in the bodies natural a-MSH are converted in the production of Melanotan 1 increasing stability. The melanotropin peptides to a larger extent can influence pigmentation in the body. If melanotan peptide therapy is combined with UV-B light, it stimulates melanocytes production of melanin and specifically the production of eumelanin. Melanin works effectively in absorbing, reflecting and refracting light to preventing cellular damage in the skin. It also transforms cells to produce dark protective melanin which ultimately helps in reducing sun damage done to UV exposed skin. On the other hand, eumelanin is produced over pheomelanin pigment that after injecting offers greater tanning ability levels. However, melanotan only works when injected below the skin (subcutaneously).

Also known as afamelanotide, the half-life of Melanotan peptides is very short. It is being developed in implant form that contains control discharge effecting melanin density for dermatology use. From human lifestyle point of view, we can say that melanocortins can be one great revolution in cosmetic treatment including Botox, Viagra and much more. Although clinical trials are still going on to check the effectiveness of melanotan in bringing approved results to people.  Slight effects like nausea and flushing are common after taking subcutaneous injection of melanotan. There are specific skin types and accordingly the dose of Melanotan 1 is taken to get effective and safe results.

Melanotan (1)

Melanotan was initially created as a way to produce a organic tan base with no exposure to the sun. The original studies understood that the best method for preventing sunburns, sun-damage and skin cancer was a healthy, pure tan base. Since there are many skin types that are more likely to burn rather than tan, the analysises started to develop this peptide in an effort to create a safe way to create pure sun safety with a sunless tan.

Later, many study has expanded to determine it’s effectiveness as a treatment for sexual dysfunctions. This analysis commenced after the original trial, conducted at the college, found that three males who were taking the peptide found that the peptide not only had quick and noticeable tanning effects, but that the side effects included spontaneous erections. They also found there was a side effect of mild nausea.

The Melanotan peptide is being studied for its ability to improve and stimulate the production of Melanin in the skin. There are many potential uses for Melanotan, but the most pervasive and explorationed use is connected to providing safe, sunless tans. added researched effects also reveal that Melanotan can act as an aphrodisiac.

This distinct peptide generally works in starting a sunless tan by binding to the melanocortin receptors. This binding process causes responses that can impact pigmentation and sexual function. This process has also been shown in some studies, to effect energy and appetite.

Studies also indicate that the tanning effects that are potentially achievable via Melanotan can do more than realize cosmetic benefits. Individuals who are identified to burn easy or who have very fair skin can reduce the change of sun connected skin problems as the darker pigmentation of their skin helps shield from sun damage and skin cancer.

This versatile peptide is also being investigated for its effects on energy, appetite and libido. Earlier study has shown optimistic affect in all three regions and studies suggest it might provide benefits for athletes or individuals who are looking to increase their workout and health.

Melanotan II

Melanotan II was developed by researchers at the University of Arizona College of Medicine. Melanotan II is an analog of the peptide hormone alpha-melanocyte stimulating hormone (MSH), this hormone provides a therapeutic tan with the ability to lower the risk of skin cancer, melanocyte stimulating hormone also plays an important role in regulating sexual arousal in men and women. 

Melanotan II has the additional effect of decreasing body fat mass. Melanotan II It is a cyclic lactyam analog of melanocyte stimulating hormone with the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2.

Melanotan II is in a class of peptide hormone known as Melanocortins (MCs). Melanocortins (MCs) are multifunctional peptide hormones that regulate a diversity of physiological functions. Melanocortins (MCs) have been implicated in sexual function in animals.

A Melanocortins (MCs) analog, Melanotan II, can enhance sexual function in human males (erectile activity) and females (increased levels of sexual desire and genital arousal). Unlike other sexual-enhancement drugs, Melanotan II works at the level of the brain, thus eliciting a rather natural sexual response with minimal or no undesirable side effects. The actions of the peptide were discovered accidentally while studying the effects of the peptide and related analogs on human skin pigmentation (tanning). (Hadley ME, 2005).

Sermorelin (2)

Things to consider before using Sermorelin Acetate

Some medical conditions may interact with Sermorelin Acetate. Tell your doctor or pharmacist if you have any of the following medical conditions:

Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to sermorelin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pregnancy
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Sermorelin (1)

Sermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2 ) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH or GRF) consisting of 44 amino acid residues.

It stimulates the pituitary gland to naturally produce increased amounts of human growth hormone. Sermorelin Acetate is a truncated analog of a growth hormone releasing factor (GRF 1-44) that is naturally produced by the brain to stimulate pituitary production of human growth hormone. The increased volume of human growth hormone (hGH) produced by the pituitary gland causes an increase in the production of Insulin-Like Growth Factor-1 (IGF-1) by the liver and results in the benefits of treatment provided to the adult patient.

The purpose of adult Sermorelin growth hormone therapy is to reverse the effects of aging and secure the extensive treatment benefits described below.

The benefits of Sermorelin therapy or recombinant human growth hormone therapy include the following:

Oxytocin (3)

Scientists have discovered that the hormone oxytocin could help wallflowers overcome awkwardness in social situations
The chemical dubbed "the hormone of love" is known to increase empathy and bonding – especially parents and their children.
But now researchers have found it improves the social skills of the shy – but has little effect on those who are naturally confident.
The finding could have implications for those with severe social deficiencies, often apparent in conditions like autism.
Researchers at Israel's Seaver Autism Center for Research and Treatment and Columbia University were examining whether the hormone, which occurs naturally in the body could make us more understanding of others.

The scientists, whose research is published in Psychological Science, also measured the participants' social competency, using a test known as AQ which is usually used in autistic patients.
They found that oxytocin did improve powers of empathy – but only among those who were less socially proficient in the first place.
The more socially comfortable participants performed well on the empathetic task regardless of whether they were on oxytocin or placebo.
But less socially proficient participants performed significantly better on oxytocin, with their empathetic powers performance identical to that of the more outgoing participants.
(Richard Alleyne, http://www.telegraph.co.uk)

What should I discuss with my healthcare provider before using oxytocin?

Oxytocin (2)

How to increase Oxytocin levels
Ingestion of food triggers oxytocin release by activation of vagal afferent nerves. Most likely, it can also be released by stimulation of other senses such as olfaction, as well as by certain types of sound and light. In addition, purely psychological mechanisms can trigger the release of oxytocin. This means that positive interaction involving touch and psychological support may be health-promoting.

Oxytocin and sex
Also known as the "cuddle" hormone, oxytocin is released by both men and women at sexual orgasm.

Massage
Oxytocin can be released by various types of sensory stimulation, for example by touch and warmth. Bloodstream levels of oxytocin have been shown to rise during massage.

How it works
Oxytocin suppresses the activity of the brain region known as the amygdala, the area that processes fear and communicates it to the rest of the brain. A small sample group of 15 men inhaled either oxytocin or a placebo before performing a task in which they sorted pictures of angry or fearful faces and threatening scenes. During the test, the researchers monitored the subjects' brain activity with functional magnetic resonance imaging and found that the oxytocin group indeed had reduced activity in the amygdala.

Oxytocin (1)

Oxytocin was discovered by a British pharmacologist named Henry Dale in 1909. It was first synthesised in 1953 by Vincent de Vigneaud, an American chemist who was awarded the 1955 Nobel Prize for Chemistry for this discovery, the first polypeptide hormone to be synthesised. He also synthesised the related hormone vasopressin, which controls the body's retention of water. Oxytocin is cys-tyr-ile-gln-asn-cys-pro-leu-glu, vasopressin is cys-tyr-phe-gln-asn-cys-pro-arg-glu.

Oxytocin (Greek, “quick birth”) is a mammalian hormone that also acts as a neurotransmitter in the brain.

In humans, oxytocin is thought to be released during hugging, touching, and orgasm in both sexes. In the brain, oxytocin is involved in social recognition and bonding, and may be involved in the formation of trust between people and generosity.

In women, it is released in large amounts after distension of the cervix and vagina during labor, and after stimulation of the nipples, facilitating birth and breastfeeding, respectively. Synthetic oxytocin is sold as medication under the trade names Pitocin and Syntocinon as well as generic oxytocin.


(excerpts of) Oxytocin hormone benefits and side effects by Ray Sahelian, M.D.

Oxytocin is a hormone that helps relax and reduce blood pressure and cortisol levels. Oxytocin increases pain thresholds, has anti anxiety effects, and stimulates various types of positive social interaction. In addition, it promotes growth and healing.

Ipamorelin

Ipamorelin is a fascinating new muscle building discovery that is getting a lot of attention in the bodybuilding world. It is a synthetic peptide that has powerful Growth Hormone releasing properties. And these GH releasing properties are what is of interest to athletes and bodybuilders since they can make a tremendous difference in the amount of muscle you can grow and how quickly you burn fat.
Ipamorelin is a penta-peptide. (Aib-His-D-2-Nal-D- Phe-Lys-NH2) And, the strength it displays may very well make regular old Growth Hormone (GH) obsolete. But what athletes and bodybuilders really want to know is what is this wonder peptide capable of doing, how is it used, and how does it compare to the other GHRP peptides?

Athletes are taking Ipamorelin in a 200mcg -300mcg dosage, two or three times daily, using a tiny insulin needle to inject. They usually start with the lower dose since side effects can include headaches or what feels like a head-rush. Ipamorelin can be taken at anytime but taking it about 30-45 minutes before a workout would seem ideal because of the pulse in Growth Hormone (GH) it creates allowing for maximum growth.

Studies on the effects of Ipamorelin on bone growth, body weight, and GH release showed some interesting conclusions.In one experiment, various doses were administered over the course of 15 days to test the group's reactions.


There was a distinct and dose-dependent effect on body weight gain however, the treatment group did not show a change in total IGF-I levels. Nor did the treatment group produce serum markers of bone development. For example, the number of cells in the wide portion of the tibia (the shinbone) did not change significantly. This is a good thing because it suggests muscle growth with less potential for deformity of bone or cartilage.

GenF20

This product is based on HGH, which is the Human Growth Hormone.

Research shows that as we age, our levels of HGH decline. This decline is associated with wrinkles and laugh lines, as well as other more troubling signs of aging such as, decline in memory and focus, weakening bones, loss of interest in sex, weight gain and sluggish metabolism, lose of lean muscle tissue, and vision changes.

GenF20 Plus is a HGH releaser.

Essentially, this product encourages your body to release more HGH into your system. This blend of amino acids, peptides and nutrients are designed to launch your pituitary gland into action. The enteric coating on the GenF20 Plus ensures that the ingredients are not destroyed by your stomach acid before they can get into your bloodstream and do their job. It is believed that enteric coating increases absorption of medications by roughly 80%.

The advantages increased HGH level:
- Looked and feel younger
- Enjoy a greater sex drive
- Gain muscle tissue
- Lose fat
- Boosted metabolism
- More energy
- Increased immune system

This product contains a powerful antioxidant to rid the body of cancer cells.

Secratatropin

Secratatropin HGH is among the strongest legal HGH Releasers. Secratatropin HGH was initially designed to help professional athletes enhance their performance using herbal ingredients that imitate the results of Performance Enhancing Medicines.

Secratatropin HGH features all-natural ingredients like Alpha GPC, GABA, L-Arginine, L-Dopa Bean Extract, L-Glutamine, L-Isoleuncine, L-Tyrosine, L-Valine, L-Lysine, and L-Ornithine. Secratatropin HGH is 100% safe, 100% legal, and 100% effective.
People want the strength of prescriptions available in products you can purchase on your own. Secratatropin-HGH is a controversial and effective product for the public. Boosting your levels of HGH, which Secratatropin-HGH attempts, should help you with smooth skin, reduced fat storage, elevated energy and vitality. The active ingredients in this product stimulate your pituitary gland to generate more HGH naturally, which can have a plethora of results reaching from better exercises or helping you look youthful. Sectratatopin-HGH could be the fountain of youth.

IGF-1

IGF-1 isn't a top-secret chemical, nor is it a dangerous steroid. IGF1 is actually a natural molecular structure similar to insulin. IGF-1 is the abbreviation for Insulin-Like Growth Factor 1.Know in scientific circles as a polypeptide protein hormone, IGF-1 or Insulin-like Growth Factor 1 plays a vital role in childhood growth and stimulates anabolic effects (muscle building) in adults.

The primary purpose of IGF-1 is to stimulate cell growth. Every cell in the human body can be affected by IGF-1, but cells in muscle, cartilage, bone, liver, kidney, skin tissue, lungs, and nerves tend to be most positively affected.

There are 70 inter-connected amino acids that make up a single chain of IGF-1. IGF-1 is a hormone that is produced when the liver is stimulated by human growth hormone. When levels of HGH rise in the blood, the liver responds by producing more IGF-1. These higher "bursts" spur growth and regeneration by the body's cells, especially in muscle cells. Increases in IGF-1 levels have shown positive effects on increases in muscle strength, size, and efficiency. When you do not have enough IGF-1 in your body, whether caused by disease, malnutrition or a hormone imbalance, your growth can be stunted.

Several scientific tests have been conducted to determine the benefits of IGF-1 and thus have prompted companies to seek approval from the Federal Drug and Administration for substances that can increase the body's IGF-1 levels. Taken responsibly over time, products that increase IGF-1 can help improve muscularity and healing and recovery times. IGF-1 can also stimulate a decrease in body fat, an increase in lean muscle mass, improved skin tone and restful sleep. IGF-1 has also been documented to increase the rate and extent of muscle repair after injuries or strains. Not only do muscles recover more quickly, they also tend to return stronger and healthier than ever when levels of IGF-1 in the bloodstream are at their highest.

HGH Spray

The Human Growth Agent (HGA) Spray is a combination of herbs and amino acids. Amino acids are one of the central chemicals needed by the body to function well. They are the building blocks of proteins and serve as intermediates in protein metabolism.

The Advantages of HGH Sprays

There are many different ways to supplement your body with HGH. You can take injections, pills or an effervescent drink mix (usually in the form of a powder). But none of these options are as effective as an HGH spray. When you use an HGH oral spray, you benefit from:

-         Faster absorption - Most other types of supplements need to pass through your stomach and liver first before they get into your blood stream. Oral sprays get absorbed through the lining of the mouth and can start working almost immediately.

CJC-1295

CJC-1295 is a long-acting GHRH analog and stimulates GH and IGF-1 secretion. It will keep a steady increase of HGH and IGF-1 with no increase in prolactin. [1] CJC-1295 represents a very exciting new compound that has the potential to increase growth hormone and IGF-I secretion and effects, with a built-in safeguard (the feedback effects of IGF-I) to limit excessive elevations of GH and IGF-1 levels. Intense fat loss. Increases protein synthesis for more muscle growth. GHRHKO animals receiving daily doses of CJC-1295 exhibited normal body weight and length. Mice treated every 48 and 72 h reached higher body weight and length than placebo-treated animals, without full growth normalization.

Sequence: Tyr-DAla-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys-(Maleimidopropionyl)-NH2

Formula: C164H266N47O46

Growth Hormone Releasing Peptide (GHRP-6)

GHRP-6 (Growth Hormone Releasing Peptide – 6) is a 28-amino-acid peptide that signals the human body to begin secreting growth-hormone (GH). Growth Hormone in the human body has host of beneficial effects such as decreased body fat, increased muscle, and increased strength and stamina. The Growth Hormone secreted by the body then causes the liver to secrete the highly anabolic hormone known as IGF-1. IGF-1 also contributes greatly to the body’s ability to burn fat and build muscle. Thus, in several studies, when subjects were given GHRP-6, their muscle mass increased and their body fat was reduced significantly.

Both Growth Hormone as well as IGF-1 also has several beneficial effects on collagen and bone tissue growth, and it would be expected that by using GHRP-6, users would experience the full spectrum of benefits typically seen with the use of GH and possibly the concurrent use of both GH and IGF-1.

In several studies done in both humans and rodents, it has further been found that GHRP-6 has a rapid effect on Ghrelin. Ghrelin would appear to be involved in excess weight gain, adiposity, and insulin resistance. This occurs during both high fat as well as high carbohydrate diets.GHRP-6 is a Ghrelin antagonist, meaning that it actually fights against Grehlin in the human body, and this may be one possible mechanism by which it helps to reduce bodyfat. 

Bremelanotide (PT-141)

Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II). PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.


PT-141 is the only synthetic aphrodisiac. Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike Viagra and other related medications (PDE5s), PT-141 does not act upon the vascular system, but directly through the nervous system (hypothalamus) to increase desire. Viagra, Cials and Levitra are not considered aphrodisiacs as they do not have any direct effect on the libido. However, treatment with PDE5 inhibitors and PT-141 are known to have a synergistic effect.

Bremelanotide is a melanocortin peptide hormone. PT-141 binds to the melanocortin 4 receptor (MC4R) in particular in the brain. Nine out of ten volunteers experienced sexual arousal in trials. The aphrodisiac effects of Bremelanotide are in a class of its own. 

Bremelanotide, injected (subcutaneously), has a unique window of opportunity lasting six to 72 hours. In lab trials female rats exposed to PT-141 began "flirting" with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood.